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CGMP is responsible for the contraction and dilation of blood vessels. PDE 5 breaks down cGMP and obstructs the waft of blood. Sildenafil found in Cenforce 200 blocks the motion of PDE 5 and increases the degrees of nitric oxide with the aid of inhibiting the breakdown of cGMP. once cGMP is produced well, blood flows easily to the penis. As an increasing number of blood flows to the penis, a pressure is created. This effects in an erection.