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Tadalafil, the active component of Tadarise Pro 40, is a phosphodiesterase type 5 (PDE5) inhibitor. Upon sexual arousal, the body releases nitric oxide, which increases levels of a substance called cyclic guanosine monophosphate (cGMP). cGMP relaxes the smooth muscle in the blood vessels of the penis, allowing for increased blood flow and facilitating an erection. Tadarise Pro inhibits the action of PDE5, preventing the breakdown of cGMP and thus prolonging its effects.